Pegasus BTX: High-Sensitivity GC-TOFMS

LECO Pegasus BTX Mass SpectrometerLECO Pegasus BTX GC-MS system with autoloaderScientist loads sample into gc-ms autoloader

Redefining GC-MS Performance

Unlock a new level of sensitivity in non-targeted analyses with the Pegasus BTX and BTX 4D systems. These advanced Gas Chromatography Time-of-Flight Mass Spectrometers (GC-TOFMS) deliver full mass-range acquisition, superior trace-level sensitivity, and automated deconvolution—giving you confident results even in your most complex samples. The Pegasus BTX offers femtogram-level detection and full-spectrum data capture for comprehensive, non-targeted analysis.

Tedious source cleaning is eliminated with the StayClean EI ion source, maximizing instrument uptime. The BTX achieves spectra acquisition rates up to 500 Hz, making it an ideal partner for the narrow peak widths achieved in GCxGC separations. BTX 4D systems pair the BTX with one of LECO’s advanced GCxGC modulators, enabling more thorough characterization of complex samples.


Why Choose the Pegasus BTX Series?

Mass Spectrometer detector on white background

Superior Sensitivity for Trace Detection

The Pegasus BTX Series delivers femtogram-level sensitivity and an extended linear dynamic range (5+ orders of magnitude), ensuring even ultra-trace compounds are detected alongside higher-concentration components in one run. With high ion transmission and a novel detector design, the BTX detects analytes that previously eluded even advanced GC-MS systems.

Scientist loads sample into gc-ms autoloader

Fast, Full-Spectrum Acquisition

The BTX acquires full mass-range data at acquisition rates suitable for fast GC and GCxGC separations (up to 500 Hz). The absence of “scanning” artifacts in TOFMS yields cleaner spectra and improves deconvolution capabilities. Full-spectrum acquisition detects every ion, even when performing targeted analyses. Data files record a complete characterization of the sample that can be reinvestigated as targets evolve or new analytes of interest emerge.

Looking inside mass spectrometer at ion source connected with wires

Versatile Performance, Reduced Maintenance

The Pegasus BTX excels in a wide variety of volatile and semi-volatile analyses. Its versatility stems from the ability to achieve detection limits commonly associated with targeted methods, even while performing comprehensive, non-targeted analyses.

To support sustained productivity in every lab, the BTX incorporates LECO’s StayClean ion source, engineered for consistent performance without the need for source cleaning. By reducing maintenance frequency, laboratories can increase throughput even when working with high-matrix samples.

Scientist running a sample on the Pegasus BTX by LECO

Comprehensive GCxGC Solutions

With such fast acquisition rates, the BTX is the perfect partner for the narrow peak shapes produced in GCxGC. LECO’s BTX 4D instrument packages pair the BTX with one of LECO’s premier GCxGC modulators for improved chromatographic resolution.

BTX 4D systems featuring LECO’s QuadJet modulator achieve sub-femtogram sensitivity and offer the best chromatographic resolution. BTX 4D systems featuring LECO’s Paradigm flow modulator and Shift flow splitter provide economical GCxGC performance across the entire volatility range, in addition to supporting dual detection capabilities.

Combined with the power of LECO’s ChromaTOF software, BTX 4D systems offer premier GCxGC-MS data quality and user experience.



Core Analyses


Featured Application Notes

How the Pegasus BTX Works

The LECO Pegasus BTX is a gas chromatography–mass spectrometry (GC‑MS) system designed for the detection and identification of trace‑level organic compounds in complex samples. It is optimized for high sensitivity and robustness, making it well suited for routine and challenging applications such as environmental monitoring, petrochemical characterization, derivatized metabolites, and many more. The system is frequently paired with comprehensive two‑dimensional gas chromatography (GCxGC) to increase separation capacity for samples containing many co‑eluting components.

Samples are introduced into the system through a gas chromatograph, where volatile and semi‑volatile compounds are separated based on their interactions with the stationary phase of the GC column. In one‑dimensional GC operation, analytes elute sequentially from a single column. When configured for GCxGC, the system uses two columns of differing selectivity connected by a device called a modulator.

Following chromatographic separation, compounds enter the Pegasus BTX mass spectrometer ion source, where they are ionized by the StayClean electron ionization (EI) ionization source. The unique open-style geometry of the StayClean source prevents it from fouling due to matrix exposure – aside from periodic filament changes, most users never maintain or clean their ion source! The resulting ions are accelerated into a time‑of‑flight (TOF) mass analyzer with pulse transients up to 35 kHz. In the TOF analyzer, ions are separated according to their mass‑to‑charge ratio by measuring the time required for each ion to travel from the source to the detector.

Because the system collects full spectral data without mass filtering, both known and unknown compounds can be evaluated post‑analysis without re‑running samples.


Instrument Details

Specifications

Ionization Source
Electron Ionization (StayClean direct extraction open style)
Detector
Scintillator – Photomultipler tube with extended lifetime
Mass Analyzer
Time-of-Flight Mass Analyzer with dual stage single reflectron
Mass Range
10–1,500 m/z
Mass Resolution
> 1,100 at m/z 219
Spectral Acquisition Rate
1–500 spectra/second—up to 35,000 transients/second
Detection Limit (Helium carrier gas)
10 fg OFN with Quant S/N > 10
Detection Limit (Hydrogen carrier gas)
10 fg OFN with Quant S/N > 10
IDL
< 4 fg for 8 replicates of 10 fg OFN injected
Precision
< 5% RDS for 15 injections of 100 fg OFN
Linear Dynamic Range
5+ orders of magnitude

Models

Pegasus BTX
Pegasus BTX 4D with QuadJet thermal modulator
Pegasus BTX 4D with Paradigm flow modulator and Shift flow splitter

Model Comparison

BTX
BTX 4D (QuadJet)
BTX 4D (Paradigm)
GC Configuration
1-dimensional chromatograph
Comprehensive multidimensional chromatograph, dual-stage thermal modulator with secondary column oven, available in LN2 cryogenics or cryogen-free versions
Comprehensive multidimensional chromatograph, reverse-fill/flush (RFF) flow modulator, constant-ratio MS/FID splitter, completed automated pneumatic pressure control
Key Features
Flexible GC-MS configuration with high sensitivity time-of-flight (TOF) mass analyzer
Market-leading GCxGC performance, improved sensitivity, cryogen-free operation available
Optimized flow modulation, GCxGC, lowest upfront and lifetime costs for GCxGC
Chromatographic Resolution
Standard
Excellent (avg. FWHM 50–100 ms)
Improved (avg. FWHM 100–250 ms)
Volatility Range
Only limited by column set
C4 (butane) through column set limit (LN2) / C8 (octane) through column set limit (consumable free)
Only limited by column set
Instrument Detection Limit (IDL)
<4 fg for 8 replicates of 10 fg OFN injected
< 1 fg for 8 replicates of 5 fg OFN injected
<1 pg for 8 replicates of 5 pg ON
Linear Dynamic Range
greater than 5 orders of magnification
greater than 4 orders of magnitude
greater than 4 orders of magnitude

Options

Pyrolysis and Thermal Desportion Solutions


Instrument Support

Ensure reliable instrument performance with extensive support, training, and maintenance services. Need tailored support for your mass spectrometers? Our experts are standing by.




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