L-PAL3: Automated Sample Preparation & Injection
Automation That Powers Your Lab
The L-PAL3 Autosampler from LECO is a high-throughput, multi-mode robotic system designed to automate sample handling for gas chromatography (GC) and two-dimensional gas chromatography (GCxGC) applications. It boosts productivity with ultrafast, discrimination-free injections, supports liquid, headspace, and solid-phase microextraction (SPME) modes via automatic tool exchange, and enables unattended operation for extended sequences.
Key benefits include maximized throughput, superior reproducibility, reduced human error, and enhanced operational efficiency—making it ideal for labs across environmental, pharmaceutical, and contract testing industries. By streamlining workflows and ensuring consistent, reliable data, the L-PAL3 empowers labs to do more with less, transforming sample prep into a seamless, hands-off process.
Why Choose the L-PAL3 Autosampler?
Maximized Throughput
Run more samples in less time with a high-capacity, fully automated system built for maximum throughput. The L-PAL3 supports a wide range of injection techniques to accommodate any sample matrix with the capacity to store hundreds of samples for days of unattended operation—keeping productivity high and labor costs low.
Superior Reproducibility
Achieve consistent, repeatable results with precise, automated injections that remove technique variability by delivering the same volume and speed every time.
Bottom-sensing technology ensures even small sample volumes are drawn reliably to avoid mis-injections.
One-time method setup and intuitive software controls standardize every injection for dependable, reproducible performance.
Flexible Injection Techniques
Automatic tool exchange seamlessly switches between liquid, headspace, and solid-phase microextraction (SPME) modes without user intervention, while integrated washing and smart monitoring—through the solvent station and intelligent syringe—minimize carryover and proactively flag potential issues before they impact results.
Operational Efficiency
Make better use of staff and resources with walk-away automation that frees analysts to focus on higher-value tasks instead of routine injections. Batch scheduling and prep-ahead capabilities optimize workflow in conjunction with multitasking—such as washing the syringe during analysis—to keep operating efficiently.
With LECO, you get a fully integrated system with one vendor, further streamlining training, support, and maintenance for smoother day-to-day operations.
Instrument Applications
Core Analyses
Metabolomics Preparation Made Easier
The L-PAL3 derivatizer is an all-in-one solution that bridges the gap between complex sample preparation and high-resolution data collection. Designed specifically for the metabolomics community, the system is optimized for two-step derivatization, using integrated agitators and specialized modules to ensure every reaction proceeds to completion. By automating these manual benchtop steps, the L-PAL3 removes technique variability, allowing your lab to achieve the superior reproducibility required for large-scale metabolic profiling.
To protect your most sensitive data, the system utilizes “just-in-time” derivatization to ensure metabolites do not degrade before reaching the injection port. When paired with LECO’s Time-of-Flight (TOF) MS technology, what used to require multiple injections and complex SIM methods can now be accomplished in a single, non-targeted run. This comprehensive approach ensures that no analytes or information are lost, providing a complete chemical picture for true unknown identification.
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Ensure reliable instrument performance with extensive support, training, and maintenance services. Need tailored support for your mass spectrometers? Our experts are standing by.
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