GCxGC変調ソリューション

概要

LECO offers two powerful GCxGC modulation solutions designed to meet the diverse needs of modern analytical labs. The QuadJet GCxGC modulator is a dual-stage thermal system that delivers unmatched separation power and sensitivity—ideal for complex samples requiring the highest chromatographic resolution. Its cryogenic jets trap and re-inject analytes with precision, producing dramatically sharper peaks and up to 10x greater sensitivity than traditional 1D GC.

For labs seeking a streamlined, cryogen-free alternative, the Paradigm flow modulator and splitter offers full mass transfer and simplified operation, making GCxGC more accessible for routine workflows and high-throughput environments. Both systems integrate seamlessly with LECO’s Pegasus platforms and ChromaTOF software, providing a complete, user-friendly solution from injection to insight. Whether your priority is elite performance or operational efficiency, LECO’s GCxGC modulators empower your lab to see more, detect more, and do more.

How LECO’s GCxGC Modulation Solutions Function

When performing GC-FID analysis, most laboratories quantify compounds using the area of the FID signal. Real world samples are rarely clean and straightforward. For example, a diesel sample can have thousands of different compounds in a single injection. The more compounds in a sample, the higher the chance of coelution; this coelution will increase the FID signal, thus creating a high bias error in the measurement. With GCxGC performing two separate chromatographic separations in one experiment, the accuracy of the FID measurement is maintained. 

Due to the orthogonal nature of the separation mechanism in GCxGC, coeluting compounds are easily pulled apart in a single run. True GCxGC instruments, such as the LECO QuadJet SD, improve upon simply running the same sample through two different columns by incorporating a modulation device. Peaks eluting from the primary column are quantitatively segmented into smaller sections prior to release onto the second column. This segmenting, along with the cryo-focusing of the modulator, can deliver peak widths as narrow as 50 ms to the second column. 

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