Capture Every Clue
ChromaTOF Sync
Data Alignment and Comparison Software
ChromaTOF Sync is LECO’s advanced multi‑sample peak‑finding and alignment solution for Pegasus BT series GC‑MS data. By co‑processing entire sample sets—rather than individual runs—Sync generates a unified, fully aligned peak table that reveals similarities, differences, and chemical trends across samples. Sync 2D extends these capabilities to GCxGC‑MS datasets, delivering powerful insight even for highly complex two‑dimensional chromatographic data.
ChromaTOF Sync Benefits
Unified Peak Discovery & Alignment
Sync processes all samples in a batch together, generating a single combined peak table that captures every analyte across the set. This eliminates manual peak comparison and accelerates trend discovery across time, treatments, or sources.
All-in-One Non-Target Data Review
By extending ChromaTOF’s deconvolution and identification tools, Sync empowers users to compare chemical profiles, track feature changes, and uncover subtle variations across entire datasets—all within one interface.
Built-In Visualization & Statistics
Tile incorporates powerful metrics such as Fisher Ratio, Coefficient of Variation, and Fold Change, which help highlight chemical differentiators under different study designs—whether samples have defined groups, undefined groups, or no replicates.
Scale from GC-MS to GCxGC-MS
Sync 2D brings the same multi-sample alignment power to GCxGC-MS datasets, reducing processing time and increasing accuracy for even the most complex samples—such as food spoilage, environmental changes, quality monitoring, and biological studies.
ChromaTOF Sync Application Notes
Flavor Comparison of Indian Masalas
Flavor Comparison of Indian Masalas
Tracking Chemical Profiles of Food Spoilage with GCxGC
Tracking Chemical Profiles of Food Spoilage with GCxGC
A Comprehensive GC-TOFMS Metabolomics Workflow
A Comprehensive GC-TOFMS Metabolomics Workflow
How ChromaTOF Sync Works
The Pegasus GC-MS platform delivers sample sets with a wealth of chemical information. But, without appropriate tools, it can be a daunting task to scour these large, dense datasets for key sample set insights. LECO developed Sync to co-process BT data, leveraging chemical information in each sample to yield a single, unified peak table for the entire set. The result is an enriched user experience, with group data much greater than the sum of its parts: expect cleaner deconvoluted spectra, precise trend identification, and built-in statistical tools to accelerate conclusions
Sync was developed and tested with real-world experimental data: Retention time shifts, challenging peak shapes, and large analyte dynamic ranges are easily tamed and aligned for simplified review. Interactive plots, overlaid chromatograms, and spectral filters permit easy monitoring of chemical behavior.
Sync 2D extends automated deconvolution, peak alignment, spectral improvement, and statistical tools to GCxGC-MS datasets. The challenge of processing large batches of GCxGC-MS data has long inhibited wider adoption of the technique – Sync 2D makes the enhanced resolution and sensitivity provided by multidimensional chromatography viable for labs that require reliable, actionable results
Frequently Asked Questions
What instruments are compatible with ChromaTOF Sync?
Sync is designed for the Pegasus BT series GC‑MS platforms, with Sync 2D supporting GCxGC‑MS datasets.
Questions to be added
Can I export results?
Yes, all tables and plots can be exported for reporting, publication, or further statistical analysis.
Is training available?
Yes! To help you get up and running quickly, customers can access step-by-step on-demand video tutorials covering the key features and common tasks with LECOLearn.
What license options are available?
Sync and Sync 2D are both available as 90-day trials, annual subscriptions, and as perpetual USB licenses.
How do I update my ChromaTOF software?
Visit LECOsoftware.com to download the most up-to-date versions of all LECO software.
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